MOTS-C · COMPOUNDEDFour formulation options.
One individual conversation.
MOTS-C is an investigational mitochondrial-derived peptide. Explore the available options and discuss the evidence, uncertainties, and your individual health history with a licensed clinician.
$210/mo
Billed monthly.
$499/quarter
Approx. $166.33/mo equivalent.
$229/mo
Billed monthly.
$529/quarter
Approx. $176.33/mo equivalent.
$199/mo
Billed monthly.
$459/quarter
$153/mo equivalent.
Quarterly plans are billed every 3 months. Confirm quantities, inclusions, and terms during enrollment.
Prescription only; clinical approval and pharmacy availability required. An evaluation does not guarantee a prescription. MOTS-C is not FDA-approved.
Important safety & evidence informationUNDERSTAND THE RESEARCH
MOTS-C research explores metabolic signaling. Clinical benefits from treatment are not established.
MOTS-C is a 16-amino-acid peptide encoded by mitochondrial DNA. Early cell and animal studies examine how it participates in metabolic signaling, including AMPK, a pathway involved in sensing cellular energy. Those findings do not establish that a compounded MOTS-C prescription improves health in people.
The original research included cultured cells and mice. FDA’s 2026 review did not identify clinical studies evaluating MOTS-C administration in humans. Studies of naturally occurring peptide levels or a related analogue do not automatically establish the effects of your compounded preparation.
Research background: Original MOTS-C cell and animal study. Evidence review: FDA MOTS-C scientific review (PDF).
HOW IT WORKS
An evaluation starts a medical conversation. Treatment is never automatic.
Complete the peptides intake with your goals, health history, current medicines, supplements, and questions. Include previous peptide treatments and any reactions.
A licensed clinician reviews your information and discusses uncertainties, alternatives, and whether any prescription is appropriate. They may request more information or recommend another approach.
If prescribed, review the exact formulation, directions, monitoring, and follow-up with your clinician and pharmacy. Ask questions before beginning or changing a medication.
BEFORE YOU BEGIN
Your clinician and dispensing pharmacist confirm the exact formulation and directions.
For the 10 mg/mL options, 4 mL and 6 mL describe the listed fill volumes. The 2 mg/mL and 5 mg/mL options have no package volume listed here. These labels are not personal dosing instructions.
Ask the care team to explain the ingredient form, concentration, quantity, route, and directions on your prescription. Do not infer a dose or schedule from the package size, the product image, or another person’s plan.
Follow your dispensing pharmacy’s handling and storage instructions, including the expiration or beyond-use date. Contact the pharmacist if a label, preparation, or storage instruction is unclear.
Clinical review and pharmacy availability determine whether treatment is offered. Confirm quantities, inclusions, renewals, and billing terms during enrollment. A billing interval does not establish a treatment schedule. See our Compliance page, Cancellation Policy, and Refund Policy.
READ BEFORE CONSIDERING TREATMENT
Human safety information for MOTS-C is inadequate. This overview is educational and does not replace your clinician’s assessment.
Compounded MOTS-C has not undergone FDA premarket review for safety, effectiveness, or quality. An HHS interim policy describes conditional enforcement discretion for certain MOTS-C acetate preparations. That policy is not FDA approval or proof of safety. Your clinician and pharmacy must verify its conditions for the specific ingredient, route, and preparation.
Read the HHS interim policy (PDF)LIMITED HUMAN SAFETY INFORMATION
FDA’s scientific review raises potential immune-response risks related to peptide aggregation and impurities. Adequate human data are lacking; the frequency and full range of adverse effects are not established. A peptide occurring naturally in the body does not mean a manufactured preparation is proven safe.
Tell your clinician about medical conditions, allergies, current medicines, supplements, and previous reactions. Discuss pregnancy, pregnancy plans, or breastfeeding before considering treatment. Ask about evidence-based alternatives for any condition you want to address.
Contact your care team promptly about new or concerning symptoms. Seek urgent medical care for breathing difficulty, face or throat swelling, or other signs of a serious allergic reaction. Call 911 for a medical emergency.
Follow only your own prescription and confirm monitoring and follow-up with the care team. Do not replace a prescribed diabetes medicine, other established treatment, or regular clinical care with MOTS-C on your own.
Sources checked November 12, 2026: FDA MOTS-C scientific review (PDF) and HHS interim policy (PDF). Requirements may change; the care team must verify current conditions.
Monthly plans are billed monthly; quarterly plans are billed every 3 months. Confirm quantities, inclusions, and terms during enrollment.
The options are 10 mg/mL in 4 mL or 6 mL sizes, plus 2 mg/mL and 5 mg/mL concentrations. Package volumes for the latter two are not specified here. Your clinician and pharmacy confirm the exact preparation, prescribed dose, route, and schedule.
MOTS-C is a mitochondrial-derived peptide studied in cellular metabolism and aging-related research. Preclinical findings explain scientific interest; they do not establish benefits from treatment in people. See the research overview above.
No. MOTS-C is not FDA-approved. A prescription or conditional compounding policy does not establish approval or proven safety. Review the safety and compounding information above.
No. Research measuring the body’s own peptide levels is different from giving a manufactured product. Formulation, ingredient identity, purity, and route all matter. A related analogue is also a different preparation.
No. Do not treat MOTS-C as a replacement for physical activity, nutrition, or established care. Discuss your goals and appropriate alternatives with your clinician, and do not change existing medication on your own.
No. It describes concentration: the amount in each milliliter. The listed 4 mL and 6 mL sizes describe volume. Your prescribed dose, route, and schedule must come from your clinician and pharmacy.
YOUR NEXT STEP
Share your health history and questions with a licensed clinician.
Prescription only. Subject to clinical approval.