BOXED WARNING / THYROID TUMORS
A serious risk to discuss.
Semaglutide caused thyroid tumors in animal studies; human risk is unknown. Do not use it with MTC (medullary thyroid cancer) in your own or family history, MEN 2, or a serious allergy to semaglutide or its ingredients.
Side effects & precautions
Common reported effects include nausea, diarrhea, vomiting, constipation, abdominal pain, headache, fatigue, indigestion, dizziness, bloating, belching, and reflux. This is not a complete list.
Serious risks include pancreatitis, gallbladder problems, dehydration-related kidney injury, severe digestive symptoms, severe allergic reactions, and low blood sugar, particularly with insulin or sulfonylureas. These medicines are not recommended for severe gastroparesis. Discuss any history of diabetic retinopathy and any vision changes.
Discuss pregnancy and breastfeeding before treatment. The label advises stopping Wegovy® at least two months before a planned pregnancy; contact your clinician promptly if pregnancy occurs. Do not combine it with another semaglutide product or another GLP-1 receptor agonist. Tell anesthesia teams about its use before procedures.
Delayed stomach emptying can increase aspiration risk during anesthesia or deep sedation. Tell every procedural care team about treatment; they determine any required adjustments.
Seek urgent care for severe persistent abdominal pain or signs of a serious allergic reaction. Call 911 for a medical emergency.